منابع مشابه
Side effects of cimetidine.
Cimetidine, an H2 receptor antagonist, is widely used in the treatment of duodenal ulcer, ZollingerEllison Syndrome (Binder et al., 1978; Winship, 1978; Ippoliti et al., 1978; Gray et al., 1978; Lc Canthy, 1978) benign gastric ulcer, gastric erosions and oesophagitis (Freston, 1979; Frost et al., 1977; Englert et al., 1978). In human beings it has a circulating half life of disappearance of 123...
متن کاملCimetidine and renal failure.
Introduction Cimetidine is a recently introduced but widely used histamine H2-antagonist. It is known to produce significant increases in plasma creatinine in normal people but the increased values usually remain in the normal range (Burland and Simkins, 1977). In clinical trials a tendency for plasma creatinine to rise, particularly in patients treated with high doses of cimetidine, was found ...
متن کاملGynaecomastia associated with cimetidine.
Gynaecomastia has occurred unilaterally or bilaterally in five out of 25 male duodenal ulcer patients after more than four months treatment with cimetidine 1.6 g daily. All elected to continue treatment to 12 months and their breast enlargement regressed rapidly and disappeared after stopping treatment. During treatment all patients were found to have normal concentrations of plasma testosteron...
متن کاملantagonists-cimetidine and ranitidine
Few drugs have so rapidly gained an established place in modern medicine as the histamine H, receptor antagonists. As a result of the inventiveness of James Black and his colleagues, the theoretical concept of a second class of histamine receptors became a therapeutic reality. The failure of classic antihistamine drugs (more appropriately H1 receptor antagonists) to block the actions of histami...
متن کاملCimetidine and thrombocytopenia
The control subjects had recently attended the fracture clinic and were otherwise healthy. They were matched with the patients for age (± 5 years), sex, social class, and marital status and were not significantly different from the patients in height or weight distribution. The controls were interviewed about their diet in the same manner as the patients. The statistical significance of differe...
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ژورنال
عنوان ژورنال: Gastroenterology
سال: 1979
ISSN: 0016-5085
DOI: 10.1016/s0016-5085(79)80025-6